Anyone know any interesting facts about klonopin?

Question

Anyone know any interesting facts about klonopin?
ex. did anyone famous use it?

Answer 1

Clonazepam is a chlorinated derivative of nitrazepam.[3] Clonazepam is classed as a nitrobenzodiazepine along with nitrazepam and flunitrazepam.[4] Aromatic nitro-containing compounds such as clonazepam produce superoxide free radicals during cellular metabolism by endothelial cells. The nitro anion radical produced during clonazepam metabolism rapidly reacts with oxygen to form the free radical superoxide.[5][6] Benzodiazepines, including clonazepam, bind to glial cell membranes with high affinity.[7][8]



Clonazepam decreases levels of acetylcholine[9] and decreases prolactin release.[10] Clonazepam is chemically related to quinazolines and is a hapten.[11] Clonazepam induces melanogenesis in melanoma cells via binding to high affinity sites and modulating cell differentiation.[12]



One milligram of clonazepam is approximately equivalent to twenty milligrams of diazepam.[13] Because of its powerful anxiolytic properties, it is said to be among the class of "highly potent" benzodiazepines. Although benzodiazepines are valuable in the treatment of anxiety disorders, they carry a high potential for physical and psychological dependence with profound withdrawal symptoms, especially if discontinued abruptly or over rapidly in certain individuals. Caution is advised when taking this or any benzodiazepine medication longer than a few weeks.



Clonazepam appears to also have a secondary effect on the neurotransmitter serotonin.[14] It has shown itself to be highly effective as a short-term (3 weeks) adjunct to SSRI treatment in obsessive-compulsive disorder and clinical depression in reducing SSRI side effects with the combination being superior to SSRI treatment alone in a study funded by the manufacturers of clonazepam, Hoffman LaRoche Inc.[15] Similar results have been found with some other anxiety disorders, but the role of the serotonergic effects enhancing the action of the SSRI treatment remains unclear in these cases due to clonazepam's primary anxiolytic mechanism of action.

Answer 2

Are you thinking it is some kind of designer drug? It's prescribed mostly for anxiety "problems" and it is supposed to be addictive! It is also prescribed for other uses. If you would like to read more about klonopin go to webmd or just google klonopin. It's not some powerhouse drug if that's what your thinking.

Answer 3

It is used to treat panic attacks - I don't know of anyone famous who used it, but I know some-one who should have



'Captain Mainwaring' Dad's Army (UK)



Famous cry 'Don't panic, Captain Mainwaring, don't panic.' Corporal Jones(?)

Answer 4

not sure...but I take it for anxiety...works like a charm and helps me sleep better!